Patient Comments: Eosinophilic Fasciitis (Shulman's Syndrome) - Symptoms and Signs


What symptoms and signs did you experience with eosinophilic fasciitis? Submit Your Comment

Comment from: MedStudentEF, 25-34 Male (Patient) Published: March 10

The most noticeable symptoms of eosinophilic fasciitis were what felt like acute onset of carpal tunnel syndrome and swelling (with severe pitting) in my legs and feet. This was accompanied with extreme fatigue and the feeling of lactic acid buildup in all of my muscles. All this occurred around the time I was diagnosed with Hashimoto’s thyroiditis.

Comment from: Paula, 55-64 Female (Patient) Published: March 29

Muscle pain in calves and glutes was my first symptom of eosinophilic fasciitis. I had clumsiness, tripping, difficulty getting up and down from floor 6 to 9 months prior to my diagnosis. Swelling and stiffness throughout, especially all four limbs, including fingers and toes started 2 months before being diagnosed.

Comment from: Bacci, 45-54 Female (Patient) Published: July 24

I had swelling in feet and legs initially with eosinophilic fasciitis. Strange muscle sensations, burning as if exercising but only lifted a blanket. The doctor removed the statin medicine to no help. I had pitting edema in ankles, hands, elbows and knees, and swelling wherein I couldn’t bend. Eventually I went to the clinic after a false diagnosis of fibromyalgia by the local rheumatologist. Prednisone brought immediate relief, methotrexate limited relief as they up the dose every time I reduced prednisone. I am still in the process of finding the right safe dose for each.

Comment from: Lucille, 55-64 Female (Patient) Published: January 12

I experienced a swelling of the legs (to the knee only) and feet, and my right arm from wrist to elbow, so much so, I tried to keep it covered up. This event happened (coincidentally perhaps) after a 5 hour flight. I noticed my feel swelled on the plane and never went back to normal. I did not experience pain. I had a rash also in my mid-back area. A rheumatologist diagnosed it as eosinophilic fasciitis but ordered a biopsy to confirm. Prednisone was prescribed thereafter and almost immediately the symptoms lessened. I was on a very strong dose initially but slowly dropped to a lesser dose and then weaned off. Within approximately 4 years of this event I was diagnosed firstly with rheumatoid arthritis and shortly after with osteoarthritis.


The term arthritis refers to stiffness in the joints. See Answer