Patient Comments: Endometrial Biopsy - Experience


Have you had an endometrial biopsy? Please describe your experience. Submit Your Comment

Comment from: Sandy , 45-54 Female (Patient) Published: July 07

I went in for a consult totally unprepared for this endometrial biopsy procedure and I thought I would die. Three times she had to do it! My question is if anyone has felt drained after. I haven’t felt myself in three days. Just no energy.

Comment from: Doctors lie, 25-34 Female (Patient) Published: July 07

I took lorazepam before my endometrial biopsy. It was the worst physical pain I have ever felt, compounded by the fact that I was told it may be 'uncomfortable' made it psychologically horrible as well. I'm afraid of every medical procedure now because I think I'll be lied to again. I screamed, and begged him to stop. I pooped on myself and fainted. If I ever have to endure this again I would demand anesthesia.

Comment from: quiltblox, 55-64 Female (Patient) Published: June 23

Endometrial biopsy is the most excruciating pain I have ever had. I have had three children without pain medicine, except a small amount at the very end with my first one, and none of it compares to the pain of the endometrial biopsy. I screamed so loud. They want me to have another one now and I am terrified. I have an anxiety disorder, which includes a fear of doctors and procedures. I am living on lorazepam, which by the way, does not work for pain. I am trying to find a doctor in my area who will anesthetize me.

Comment from: THSB, 25-34 Female (Patient) Published: June 17

I had an endometrial biopsy today. I was told by the nurse there would be some cramping, and to take some Motrin. I asked if I needed to bring my husband, and she said no, I’d be in and out. Ok... first, I was not prepared for how excruciating this was going to be. I’ve had a child, and it felt like giving birth without an epidural! My doctor was unable to open my cervix even with numbing medicines... so I have to get a D and C. I’m currently bleeding and cramping so bad.

Comment from: Holly, 35-44 Female (Patient) Published: June 09

I had my second endometrial biopsy today. The first was three years ago. My doctor prescribed me Serax to relax me and I took 800 mg of ibuprofen. He also numbed my cervix. The cervical block stung for about 5 seconds (a 2/3 in the pain scale). I didn’t feel him enter my uterus. I felt very minimal cramping when he was taking the sample (a 1/2 on the pain scale). I think having my cervix numbed made all the difference in my experience both times. Ask for numbing, it helps significantly.

Comment from: Alliely, 45-54 Female (Patient) Published: June 09

I had my second endometrial biopsy today. The first was three years ago. My doctor prescribed me Serax to relax me and I took 800 mg of ibuprofen. He also numbed my cervix. The cervical block stung for about 5 seconds (a 2/3 in the pain scale). I didn’t feel him enter my uterus. I felt very minimal cramping when he was taking the sample (a 1/2 on the pain scale). I think having my cervix numbed made all the difference in my experience both times. Ask for numbing, it helps significantly.

Comment from: PM, 35-44 Female (Patient) Published: May 20

I had an unplanned (as in I wasn't informed until this appointment today) endometrial biopsy for pre-operative test for a hysterectomy. The procedure itself was severely painful but completed in seconds, no medicines. The pain afterwards... excruciating! Feels like terrible horrible labor pains, and I have nausea and bleeding, it has been hours after the procedure.

Comment from: Joan, 55-64 Female (Patient) Published: May 11

I had my endometrial biopsy done today. I have a great obstetrician/gynecologist, gave me misoprostol and Advil before, gave great explanations, and was careful. Four attempts past the cervix, 25 minutes, pain 5-7 on 1-10 scale. I breathed and they talked me through the pain. Better than late stage endometrial cancer or unnecessary anesthesia in my honest opinion. I was not tempted once to tell her to stop. After reading comments before I went I decided to get a friend to drive (in case it was worse). I was assured that doctor would stop if I asked. Don't panic!

Comment from: Bri15, 25-34 Female (Patient) Published: April 23

I had issues in the past and had trigger point injections (multiple shots of intense stinging pain in my vagina). I have a high pain tolerance but this endometrial biopsy was so different. I was told to take 800 mg ibuprofen beforehand so I assumed there would be cramping. Well, 25 minutes of intense cramps and pinches and swabs later, I was crying and nauseous. Not pain, but more like so uncomfortable that you think you may pass out, for 20 minutes straight. I felt unprepared for the process mentally, so just prepare.


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Comment from: Julie, 45-54 Female (Patient) Published: March 20

I just had an endometrial biopsy today. If you're having one, please ask about pain relief or sedation. I was told there would be some cramping... and I had three kids, so I figured I could handle this. But it was painful, not just uncomfortable. I had what doctor called a vagal response and got very dizzy, and then, after the procedure, I vomited. Doctors should really prepare people better for how this feels and offer more pain relief than taking ibuprofen ahead of time, which I did.

Comment from: Hssmith, 35-44 Female (Patient) Published: March 17

This is the week after endometrial biopsy. I had it done on Monday. First 24 hours after the procedure there was intense cramping that felt like active back labor, plus spotting. Not sure why I felt it in my back. Motrin didn’t stop it but I could deal with it; had 3 kids. Day 2 I had frequent cramps and spotting. Day 3 I used a tampon as the doctor said I could; cramps were gone. Day 4 my cervix felt irritated so I quit with the tampon. Day 5 bleeding stopped. Day 6 nothing - back to normal. I was very tired all week from the stress of it all.

Comment from: Melissa, 35-44 Female (Patient) Published: March 17

I just had an endometrial biopsy done and oh my goodness it hurt so bad! I was told it would just be uncomfortable. Not so much! I’m on day 4 afterwards and still sore. I had bleeding, clotting, lots of bloating, burning and felt very sore. Good Luck!

Comment from: Hssmith, 35-44 Female (Patient) Published: March 11

My doctor gave me 200 mg Cytotec that helps dilate the cervix, to take 4 hours prior to the endometrial biopsy. I spent a few hours cramping. Took 1000 mg Motrin upon arrival. The doctor tried to get the tube in but my cervix was still closed so she gave me numbing shots to get the tube past my cervix. I did not feel the actual suction of tissue from my uterus as I was warned would be a big cramp. The cramping afterward has been constant for a few hours even with Motrin. Light bleeding. Overall not horrible. Anxiety was the worst.

Comment from: adobe711, 25-34 Female (Patient) Published: March 09

I inserted a 400 mg misoprostol 12 hours before my endometrial biopsy, and had 1 leftover codeine pill from 2015 (whoops). Previously I had a cervical punch biopsy before at the same gynecologist’s, and felt no pain whatsoever. Endometrial biopsy took under 1 minute, pinched/hurt a little and there was pressure, but overall I've had worse stubbed toes. Hyped myself up with fear for nothing.

Comment from: Annelieskl, 45-54 Female (Patient) Published: March 09

I had a very positive experience today with my endometrial biopsy. The doctor went in twice for separate samples. It was a little uncomfortable but not much worse than a Pap smear. I have had cramping and bleeding since, but less than (my ferocious kind of) menstruation. I was prepared to focus and breathe as in labor but didn't need to.

Comment from: Li, 35-44 Female (Patient) Published: March 06

I had an endometrial biopsy yesterday (without knowing ahead of time) and although I won't downplay the pain, because it was excruciating. The process was not as scary or bad for me as some of these other women have experienced. There was a lot of bleeding and I'm still in pain today, and I have been crying a lot! I'm not sure why but my emotions feel completely out of whack (I'm assuming due to the stirring up of hormones, the opening of the cervix and scraping of the uterus causes).

Comment from: teena, 75 or over Female (Caregiver) Published: March 05

I hope health professionals are reading these posts. My 76 year old mother had an endometrial biopsy yesterday. The doctor did not warn her about the pain she was going to experience, and sedation was not an option due to her heart condition, but no other pain relief was offered prior to or after the procedure. Mum screamed at the doctor to stop, she kept going, and mum starting swearing at them to stop, the doctor kept going. Mum said the pain was worse than when she broke her back. Mum remains in shock and is distressed.

Comment from: Strong woman, 45-54 Female (Patient) Published: March 03

I had an endometrial biopsy today and the doctor did explain I may have some discomfort while they are scraping the inside of my uterus. I was not prepared for the pain I encountered with this. The doctor first removed a polyp which was uncomfortable. The doctor then took 2 samples for biopsy which was very painful. The doctor then scraped inside of my uterus which was extremely painful. The procedure took 30 minutes from beginning to end. Twenty of the 30 minutes were painful beyond a patient’s tolerance.


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Comment from: just get it done, 45-54 Female (Patient) Published: February 25

I am surprised people want to be put under for endometrial biopsy. The risk is so high. My first one was done a few weeks ago. I was going in for a consultation and then boom, I got the endometrial biopsy. It hurt so bad and I cried after. The cramp was bad after as well. Next, I get the call that they labeled my specimen wrong and I have to repeat all my tests. I was with a woman gynecologist. It still hurts but she was so quick. It was so much better. It is the next day and today is worse due to cramping. Good luck.

Comment from: Fighter, 25-34 Female (Patient) Published: February 20

I had my endometrial biopsy last 2 days. At first, after the procedure, I got bleeding and it stopped after 5 hours. Then on the next day, it started to bleed again in the evening and lasted till today, like a period. Actually I’m so frustrated that my gynecologist didn’t mention about this procedure, she only said I was going to have a Pap smear. It is painful and I feel like I am about to faint. She also didn’t advise me on what I should avoid or do after procedure. I just googled it for my own sake. I did cry for this!

Comment from: alsopissedoff, 45-54 Female (Patient) Published: February 19

I didn't know beforehand that I was getting this procedure. I was told the endometrial biopsy would be like a Pap test with some discomfort. It hurt like blazes, she took the sample and then took another one. I looked over and saw the instruments covered with blood on the side table. The doctor and student left the room, I got up and felt like I was going to faint. I started crying, no one came to check up on me before I left, and I cried all the way out of the office and on the whole walk home. A total nightmare.

Comment from: pissedoff, 25-34 Female (Patient) Published: February 12

I had an endometrial biopsy yesterday (an unsuccessful one). I was not prepared for pain on this level. I was not warned at all and given no medication. When I asked the nurse if it would hurt, she told me there would be light cramping. I was expecting something like a colposcopy (painful but not near the level this was). This felt barbaric, like medieval torture. I was in tears anytime I thought about it for the rest of the day. Like many others, I can't believe this is done without anesthesia.

Comment from: kimwhitt, 55-64 Female (Patient) Published: February 10

I agree with those who say they had no idea that endometrial biopsy would cause so much pain! I am 61, have 5 children, 2 are twins, have delivered totally natural and endured C-section while awake and half sedated as all pregnancies were breech, even the twins. I almost kicked that little sweet female doctor in the head to make her stop. I have never felt such pain.

Comment from: Snow Ninja, 45-54 Female (Patient) Published: February 05

My general physician attempted to do a uterine endometrial biopsy on me 2 days ago. She gave me little instruction but just in case, I took 4 Advil tablets beforehand because I had a feeling it would hurt, and boy was I right! The pain was indescribable and I am still cramping and bleeding two days later and having flashbacks of her trying to jab though my cervix. I happen to also be in medicine and I cannot believe this procedure is even allowed without serious medicines.

Comment from: AngelaMarie, 19-24 Female (Patient) Published: January 31

I just had an endometrial biopsy and I felt like I’ve just been violently assaulted. I was not even remotely prepared for the pain I was about to experience. “Mild cramping” they said. “Take an ibuprofen” they said. She began the procedure and I screamed and jumped back on the table. I started crying uncontrollably and I begged her to stop, she didn’t. “Almost done” she said. I left feeling traumatized. I couldn’t even think straight enough to ask any questions that I would have otherwise asked. Why don’t they prepare you for this!

Comment from: bethygal83, 35-44 Female (Patient) Published: January 30

I had an endometrial biopsy done today. It was awful. My endometrial lining is thickening and I also have a fibroid. Doctor suggested to do a biopsy after heavy bleeding and pain. I said ok. I had no clue what I was in for. It hurt terribly. Felt like the doctor was ripping out my insides. Very heavy pain and cramping. He did it twice and it was awful I didn’t even know that you could ask to be knocked out for this. Or take pain medicines beforehand or I would have.

Comment from: CBW, 45-54 Female (Patient) Published: January 29

Doctors should be honest about how painful endometrial biopsy is. When she said she can give me laughing gas, I should have known. But I asked for Percocet and Valium instead. I took a Percocet 3 hours before and it still was horrible and extremely painful. Seems like the 2 misoprostol inserted in my vagina didn't dilate my cervix as she asked the assistant for the dilator. That's when the pain began. Plus I had sat for almost an hour before the biopsy. My advice is, be thoroughly sedated.

Comment from: Brenda, 55-64 Female (Patient) Published: January 29

I wish I had been warned. I left the office feeling assaulted and victimized after my endometrial biopsy. My doctor only suggested I take an NSAID prior. I was very close to fainting and in tears when on the 4th attempt to enter my uterus all the way, I had to stop, the pain was unbearable. The procedure was not completed. There has to be a more humane way for women who experience this much pain during the procedure.

Comment from: MJ, 55-64 Female (Patient) Published: January 29

I went to my obstetrician/gynecologist today and the gynecologist told me she would do an endometrial biopsy. It was excruciatingly painful and I begged her to stop! I had no idea it would be that painful. About 10 minutes of agony. By the way, she did not stop after I said 'please stop' repeatedly. Barbaric procedure with no pain medication!

Comment from: Kristeen, 55-64 Female (Patient) Published: January 24

I had my second endometrial biopsy yesterday. I took a Tylenol 3 plus a lorazepam and still nearly passed out with the pain. I even cried. This is the most barbaric procedure to do without anesthesia. I told her never again without being knocked out. Doesn’t help that my gynecologist is very matter of fact, not the best bedside manner. Everyone is different but for me it was torture.

Comment from: Donnatella, 45-54 Female (Patient) Published: January 09

I had an endometrial biopsy this morning. I can honestly say that it was nothing to be in the least bit nervous about! The night before, my doctor prescribed a one low dose pill of misoprostol which ripens the uterine lining and dilates the cervix. I had no issues with that, no bleeding and no cramping. I went in this morning and the procedure was easy - a slight pinch and just a bit of pressure. Nothing to get nervous about!

Comment from: Cornelia, 45-54 Female (Patient) Published: December 11

My endometrial biopsy preparation was as follows. I started a week before with castor oil packs (google it, it is great). The night before I had a light dinner (matzo ball soup, and a small quesadilla). In the morning, 3 hours before the procedure, I ate 1/2 banana, then took 600 mg of ibuprofen, waited 15 minutes and then drank 1/4 cup of coffee. Thirty minutes before the procedure I took another 200 mg ibuprofen. I also had a stress ball and I did my Lamaze breathing. It felt like stronger period cramps and a bit of a burn.

Comment from: Hermoine, 55-64 Female (Patient) Published: November 26

I had the hysteroscopy and endometrial biopsy done the same day. My doctor who I just met, her nurse, and an ultrasound technician kept commenting what a brave woman I was, because I did not cry, scream or swear during the procedure, and after reading everyone’s comments what they went through I can see why! What hurt was opening my cervix. Found out I did have cancer after telling doctors for 3 years something felt wrong. I went to my appointment by myself.

Comment from: JG, 45-54 Female (Patient) Published: November 19

It helped a lot to read the stories on endometrial biopsy, as my doctor also suggested to take 600 - 800 mg of Motrin or Advil. I felt it was a good idea to also take Valium (diazepam) since this medication not only keeps you calm but also relaxes your muscles. I took 800 mg of Advil 45 minutes before, 5 mg of diazepam 30 minutes before, and another 5 mg just before I got to the office. My procedure went well and pain was acceptable. Breathing method helped. No cramping afterward. Little spotting. Felt fine after. You need a driver.

Comment from: Booboo, 45-54 Female (Patient) Published: November 15

I had an endometrial biopsy yesterday. After reading these comments I almost cancelled my appointment. I was so scared. I was able to prepare by taking Motrin and a muscle relaxer beforehand. My doctor does not use the tool to grasp the cervix. She just went in with the catheter and pipette and it took maybe 30 seconds. Strong cramps, but I didn’t swear once. Everyone is different and feels pain differently. If you need the biopsy, prepare for it and just do it.

Comment from: Mrs. D., 55-64 Female (Patient) Published: November 14

After reading many accounts of severe pain with endometrial biopsy, I was scared. My husband was allowed to go with me, which helped a lot. I know I was blessed with a fairly easy time and that's why I'm writing. Not all women have horrible experiences. Yes it hurt - pain that was abrupt and that could be described as stabbing, but it didn't hurt like that for the entire time. I think there are many factors and everyone is different. Don't assume the worst; in my case, it was over quickly with little post-pain.

Comment from: Unhappygirl, 55-64 Female (Patient) Published: October 28

I wish I hadn't gone on my own for endometrial biopsy. It was terrifying. You have to walk into an operating theatre fully awake. I took some codeine before I arrived but it wasn't enough. I cried my eyes out and the most uncomfortable part for me was the feeling of something being blown into my womb. I just walked out afterwards with no aftercare, no offer of someone fetching me a drink. I went to a cafe and went into a panic attack and relived the whole experience in bed that night.

Comment from: Belle, 55-64 Female (Patient) Published: October 28

I am 61 years old and gave birth to two children with no pain medicines. My doctor did a paracervical block and then did the endometrial biopsy. I cried out in pain and she apologized and suggested deep breathing which helped. I was very dizzy and shaky, and I went home to rest on the couch. I ate a mild dinner of chicken soup and bread. In the middle of the night I woke up vomiting blood. The next day I went to the general surgeon for consult. Diagnosis was stress reaction to the biopsy! I thought maybe I had an ulcer!

Comment from: Jane, 75 or over Female (Patient) Published: October 25

In my case the pain (not cramping) started in the early morning of the day following the endometrial biopsy procedure. Pain still persists on day two. I was told to call back in 2 weeks for the result.

Comment from: Jeanne, 35-44 Female (Patient) Published: October 21

I had an endometrial biopsy yesterday. Excruciatingly painful. I really needed either anesthesia or something to numb me for this. I felt like I was back in the 1800s. This procedure seems so archaic to me. The doctor didn't even explain what to do to take care of it when I got home. I had to Google what precautions to take. Do your research on how to care for yourself after the procedure because the doctors act like it's no big thing.

Comment from: Banzaibetty, 45-54 Female (Patient) Published: October 15

I had an endometrial biopsy yesterday after discovering polyps in my uterus. It hurt terribly and I had to change my underwear when I got home (almost bled through my pants), and put on a pad. I have brown clots coming out 36 hours later, plus cramping.

Comment from: Twobusymom, 55-64 Female (Patient) Published: September 30

I had my 3rd endometrial biopsy today. The first two were about a year ago. The very first time was uncomfortable but not horrible. The doctor did not get enough tissue, so I had to go back a few weeks later to have it done again. The second time was excruciatingly painful (clearly she scraped harder). Today, when I left, I started sobbing as soon as I got to my car. This procedure should not be done without anesthesia.

Comment from: JRblue, 45-54 Female (Patient) Published: September 24

So glad I hadn't researched what entailed. I would've been terrified by the comments. Yes, the endometrial biopsy hurt terribly but didn't compare to some of descriptions. I am guessing it is painful for all, but the level of pain is based on the characteristics of the individual and perhaps what's needing to be done. My experience was very painful, but dull, stabbing jabs (3 or 4 times) in the lower abdomen, lasting 20 to 30 seconds. I became lightheaded, and it triggered a migraine. I rested 15 minutes with the lights out before I dressed. I was lightheaded again. I was given Motrin, and I rested 30 minutes more. I drove home and had a dull ache for 1 hour. No other symptoms.

Comment from: Lmp , 25-34 Female (Patient) Published: September 19

I had an endometrial biopsy done yesterday. The nurse asked me if I’ve had kids and I said no, and she said beware, it might hurt. I thought I could deal with this. I’ve had kidney stones which was really painful but this biopsy was on another scale. The moving around up there wasn’t the issue, it was when he was using the knife. No painkillers, and no anesthetic. I cried so hard after and it was probably the worst experience ever.

Comment from: PainInPa, 35-44 Female (Patient) Published: September 19

I had an endometrial biopsy this week. I have adenomyosis (endometriosis inside the uterus) and polyps. I was told this test was necessary before I have a hysterectomy. I took Motrin and Xanax 2 hours before. It didn’t help one little bit. This was hands down the most painful experience I’ve ever had. I almost passed out and puked during the test. After 4 tries, my cervix still wouldn’t open enough to pass the pipette through and I apparently have stenosis of the cervix. So no test results.

Comment from: Debra, 35-44 Female (Patient) Published: September 11

I had an endometrial biopsy today and was not expecting more than a Pap before the doctor expressed the need for the biopsy. I feel bad that you all have had such horrible experiences. In fact, I feel like I missed something because I didn’t feel any cramping or much of anything other than a slight discomfort and light spotting afterwards.

Comment from: Twoforme, 45-54 Female (Patient) Published: September 11

I had an endometrial biopsy done today. It was one of the worse experiences I've ever had. I was told to take Ibuprofen before. I did take 400 mg and the doctor said it would have been worse if I hadn't taken it. I don't know why they don't give you Valium or some other type of drugs (or numbing) before they do this procedure. I could feel everything she was doing to me and it hurt badly. The doctor said I would have some cramping, but it felt like labor pains (I have 2 children).

Comment from: SDS, 45-54 Female (Patient) Published: September 06

I wonder if anyone experienced depression after their endometrial biopsy. And if anyone experienced horrible periods since; who had had no problems before. The doctor insisted on this or a D and C, wouldn’t listen to me. She insisted I have this done. Never will again. Hysterectomy or nothing. I’m done.

Comment from: Jan, 65-74 Female (Patient) Published: September 04

I had an endometrial biopsy done a few days ago. Although the doctor and nurse were very kind and reassuring, it was a very painful procedure. I was not warned that I would be having this done and was not offered any analgesia. I felt faint at one stage and also on the bus home. I was not warned that pain and bleeding would follow. It is now 6 days since the procedure and I am still spotting and having cramps. Women should not have to suffer this painful procedure without sedation or anesthesia.

Comment from: Jbennett74, 35-44 Female (Patient) Published: September 04

It is 4 years later and I'm still trying to figure out why my life spiraled downhill after having a uterine biopsy. I can attest to the horror stories of how unexpectedly painful the endometrial biopsy was. I was also lied to/grossly misinformed, and definitely not anticipating that level of torture. It felt like a bad dream, as though my organs were being harvested while I was restrained without any sort of anesthesia. Total nightmare then, and ever since.

Comment from: Carrie, 45-54 Female (Patient) Published: September 04

I had an endometrial biopsy yesterday. It was my 4th. The other 3 were nothing like yesterday. I was glad a friend went with me because the procedure hurt badly. My other 3 were mild cramping and a little discomfort. So, I was surprised at the level of pain. She did say she was also doing a little D and C too. I think that is where the intense stabbing pain came from. She stopped immediately and said, ‘you will have to be put under for this,’ so the endometrial biopsy in itself is not fun, but manageable.

Comment from: Lulu, 45-54 Female (Patient) Published: September 04

I had an endometrial biopsy done earlier today. It was the most painful experience of my life. To have this procedure conducted on us without anesthesia is sadistic. Never again! No one can prepare you for the amount of pain that you will endure. It is off the charts. I will definitely tell everyone I know to request anesthesia when undergoing this procedure.

Comment from: Annieb5191, 65-74 (Patient) Published: September 03

I too had and endometrial biopsy. I am 67, never had kids, so my cervix was hard to get dilated. I did have lots of pain when my obstetrician/gynecologist finally got through and got the samples he needed. But, it got better hours later. All I can say is this, and it is from a different perspective; I watched my husband take his last breath and die from cancer. Do I want cancer, no! I will need another biopsy in 6 months. I can tolerate pain for a little while, most of us can. You do not want cancer, trust me.

Comment from: CO, 35-44 Female (Patient) Published: August 28

After reading comments on endometrial biopsy, I was so terrified. It was a little uncomfortable but not bad. I talked with my nurse before and she explained there are two types of biopsies. First they suction cells out and the second they slice the cells out. The suction procedure does not hurt very much but she said the one where they slice a piece does hurt quite a bit more. My advice is to figure out which one you are having done and to take the comments with a grain of salt and not let them get you worked up.

Comment from: J, 45-54 Female (Patient) Published: August 28

I just had my fourth endometrial biopsy today. This one was by far the worst. I brought a friend and that helped. I had to be dilated more this time and it was painful, but was over in 10 minutes. I was a little shaky after and my doctor felt bad because it was a little more involved this time, my other three were not like this one. They were just mild cramping, no big deal. It’s nothing you can’t get through. I recommend taking someone to hold your hand.

Comment from: Melaus, 35-44 Female (Patient) Published: August 20

My endometrial biopsy caused horrible pain. I was lied to by the nurse. I got to the office for the procedure. I was told that I would receive numbing medication. That was a lie because when they began doing the procedure I asked and the nurse said no anesthesia is given for this. I was in terrible pain for 3 hours after and 7 days later I am still bleeding with severe cramping. I don’t think this is normal. I going to the emergency room.

Comment from: Shay, 35-44 Female (Patient) Published: August 19

I had an endometrial biopsy done today and it was the most painful thing I’ve ever experienced. I have been passing blood clots since. I’ve read the post but no one has said anything about passing clots. I’m in so much pain I can’t think straight.

Comment from: Texas GYN Patient, 45-54 Female (Patient) Published: August 14

I've had 2 endometrial biopsies done. Five years ago, pain during biopsy was like a bad period cramp, did not last very long. I recouped quickly with minimal spotting. The second one, August 8, pain was so intense, I passed out for a couple of seconds. I threw up afterwards, and was shaking. It took me about 25 minutes to recoup as I was driving myself home. Anesthesia should be applied. Many of the comments on this board are so similar. I don't know if I would go through this again, there has to be an alternative.

Comment from: Matilda, 45-54 Female (Patient) Published: August 14

I went in yesterday, didn't know the doctor was going to perform an endometrial biopsy until I got there. No numbing, no pain control. It was excruciating. I was sobbing, trembling, and trying not to hyperventilate. I'm not a wimp when it comes to pain. I cannot believe they do this with no pain management. If I ever have to do it again, they're going to have to knock me out. She took three samples from my cervix, the endometrium, and from my vaginal wall. Still very uncomfortable today.

Comment from: Tortured by biopsy, 55-64 Female (Patient) Published: August 13

I'm 59 years old, and have given birth to 2 without any pain killers. I have numerous painful health issues for over 30 years, so I understand pain. Nothing can prepare you for this! Endometrial biopsy has been described here as barbaric, well it's far beyond that. To do this procedure without knocking a woman out is animalistic, sadistic, and cruel torture. It is day 7 and the pain has not stopped. I'm sickened by the horrific pain you've all suffered, so incredibly sorry for all of you. Never again.

Comment from: Sparkling63, 55-64 Female (Patient) Published: August 12

I had an endometrial biopsy and was not told to take any medicines for pain. The procedure was very painful and I am still hurting, spotting and cramping on day two after the procedure. I never had any children and wondering if childbirth could be any more painful.

Comment from: Ani, 45-54 Female (Patient) Published: August 06

The endometrial biopsy did definitely hurt. The doctor said it would be crampy after. I had severe cramping for 3 days and some mild spotting. Then 2 weeks early a lovely period that was much more painful than normal. I have a high pain tolerance but this was not good. I feel like some women's gynecological pain is dismissed by doctors especially during procedures like this.

Comment from: Worried, 45-54 Female (Patient) Published: August 06

I am 49 years old and had an endometrial biopsy 5 days ago, which was uncomfortable but really nothing to worry about. I wasn't very sore. I carried on as normal afterwards without any pain and very little bleeding. However on the third day after, I started getting cramps and more bleeding. I wonder if this is normal.

Comment from: les, 45-54 Female (Patient) Published: August 01

I had an endometrial biopsy today, and the doctor said it would be painful but quick. Well, 30 seconds wasn't quick enough. Anesthesia should be mandatory. I have a high pain tolerance although I haven't given birth, I've had an ectopic pregnancy that almost ruptured and tubal dye test, both of these were extremely painful and this procedure today was on the same end of the pain meter. I cursed and said some not so nice things, told her to stop, and if anything else needed to be done she would have to knock me out!

Comment from: Kking19, 35-44 Female (Patient) Published: July 31

My first endometrial biopsy was done in 2017. I was awake, with no medicine or warning. I was told it would feel like mild cramping. Um, wrong! I would much rather have a child natural than another. Well, again 2 years later I have to have another biopsy but I got smart this time and told them to knock me out. They actually agreed. I am 4 hours post-operation and I can't urinate, and it feels like someone is constantly kicking me in my stomach. Thinking about going back to get checked. Will update at a later date and time.

Comment from: Funkymonkey, 25-34 Female (Patient) Published: July 30

I had hysteroscopy and endometrial biopsy done a week ago... started off with hysteroscopy. I thought this wasn’t as bad as I thought, as I was petrified. The doctor commented how well I was managing as she was having a bit of difficulty getting through my cervix. Next came the biopsies... nothing could have prepared me for how horrific it felt. All I remember is shouting no, no, stop, because it was the worst pain I had ever felt. The doctor continued to take second sample which I am sure was worse. I lay there stunned. Never again!

Comment from: Rakga, 35-44 Female (Patient) Published: July 25

I had my endometrial biopsy today and it was excruciating and extremely traumatic. Even with misoprostol the night before, 800 mg of Advil an hour before plus a Xanax, the usual 5 to 10 minute procedure took 45. My cervix was extremely narrow and the doctor could not get the tube through even with many dilation attempts and a numbing injection. I literally jumped at one point and my foot came out of the stirrup. The final attempt (4) was successful. Now the wait for the results! I will never do this without anesthesia again.

Comment from: Mel, 55-64 Female (Patient) Published: July 23

I’m 62. I had endometrial biopsy this morning for post-menopausal bleeding. The doctor took 2 samples, said it would hurt a bit and a cramp. Well, the pain was excruciating from beginning to end. It brought tears to my eyes. This evening, I am still bleeding, cramping and it burns to urinate!

Comment from: DonnaRenee, 45-54 Female (Patient) Published: July 22

I had an endometrial biopsy done today. The doctor said I would feel a cramp. It was an excruciating stabbing pain. The doctor did it twice. I screamed and could barely breathe. I would have wanted to be asleep. Still cramping now, it’s been 12 hours. I have taken ibuprofen but this pain calls for a mild pain killer. I have a scraped feeling inside.

Comment from: Co2019, 35-44 Female (Patient) Published: July 19

I had an endometrial biopsy done almost a week ago and was just checking if I could take a bath yet, when I came across this post. I had a different experience for sure. It did hurt and was very uncomfortable but I wouldn't choose to go under for it if I had to do it again. So maybe it depends on the doctor, it wasn't fun but personally wasn't as bad as people are saying (for myself).

Comment from: SilverWings, 25-34 Female (Patient) Published: July 19

The doctor was thorough in explanation of what he was doing when I had my endometrial biopsy. However, he said it felt like cramping. Um no. It hurt. A lot. Like a wasp sting on the inside. Except worse. My head swam. And that was after the ibuprofen to alleviate some of the incoming pain. We waiting 4 plus minutes to let the medicines take effect. He was very apologetic about the pain; which according to this site is normal. Anyway, not cramp like at all.

Comment from: Justme, 55-64 Female (Patient) Published: July 10

I am a 61 year old woman, nine years post uterine ablation. I had some bleeding for the first time since ablation. Abdominal and back pain for 6 months or more sent me to the physician. I had an endometrial biopsy, and yes, it was painful. I have four adult children and know what pain is. The biopsy had to be done and I’m glad to have it over. The gynecologist took her time so I wouldn’t have to have it done twice. Waiting on results.

Comment from: willow h, 19-24 Female (Patient) Published: July 03

The pain during the endometrial biopsy was extreme, but subsided to dull pain shortly after it was over. The bleeding lasted for a few hours, but not much. The cramping went away after a couple days.

Comment from: Britta, 65-74 (Patient) Published: July 02

Pain from the endometrial biopsy was excruciating, and prolonged by the difficulties encountered in cervical narrowing. Nausea and faintness were pronounced during the procedure, requiring a couple of (very painful) pauses. Insufficient tissue extracted on first attempt, so a second pass was required. That part was uncomfortable, but eclipsed by other pain! It is madness to do this without warning or drugs. This is 20 minutes of my life that will never be repeated. Why is this acceptable practice!

Comment from: I had an endometrial, 45-54 Female (Patient) Published: July 01

I had an endometrial biopsy today. One sample was removed from my cervix and one removed from my uterus. It was excruciatingly painful, and I will never do this again without anesthesia.

Comment from: Marley, 35-44 Female (Patient) Published: June 25

I had the endometrial biopsy done 4 days ago and I'm still recovering from the psychological effects. Every women should be warned this is an excruciating procedure, and should demand it be done under anesthesia. I was shocked how brutal it was and that it was presented as an easy procedure. I took 800 mg of Motrin before the procedure, and it did nothing to stop the pain I felt while the doctor was taking the sample. It felt like I was being stabbed, I screamed in pain. Really traumatized in the aftermath.

Comment from: Ann124, 35-44 Female (Patient) Published: June 19

I had endometrial my biopsy on Friday; from reading posts here I took some pain medication 1 hour prior which I think helped. However, for me, dealing with the post/after effects were more of a challenge - I knew the spotting could continue but wasn’t sure I would continue cramping afterwards. I also noticed (sorry if too much information) bowel movements after the biopsy/next day were very loose. No one warned me about this so I am not sure if it is just me or if anyone else has experienced this post biopsy.

Comment from: IN, 55-64 Female (Patient) Published: June 12

I had an ultrasound done and was called for the follow-up appointment without warning that an endometrial biopsy was going to be done. I was not even advised to take a painkiller prior to the procedure. I have a high tolerance to pain, but this pain was excruciating and horrible! It took about 5 to 6 minutes, but seemed like an hour. I felt I was stabbed from inside, many times. I will never do it again without anesthesia. In 21st century, women should not be tortured in the gynecological chair!

Comment from: Ivy3, 35-44 Female (Patient) Published: June 04

I had an endometrial biopsy procedure 2 days ago. I'm only just feeling right again. It's fast and furious. Literally 10 seconds. The doctor counted down from 10 and it was done. But they were extremely painful 10 seconds. When I sat up I could not move for a few minutes. I think I was in shock. The pain goes as soon as the catheter is out, it's only tenderness and an achy feeling after. You can’t lift anything heavy for 24 hours after. And you couldn't anyway. I felt sick and weak after. It was not what I was expecting.

Comment from: Sydney R, 25-34 Female (Patient) Published: June 03

I had an endometrial biopsy done less than a year ago and am scheduled for another one next week. I have a high pain tolerance but this was excruciating. The suctioning was the most painful part for me. I didn’t take any Advil beforehand so that could have helped. But that was something I never wanted to do again. The pain radiated all across my pelvic area into my lower back. Everyone is different so it may hurt for some and be fine for others. It’s fairly quick so you forget about the pain.

Comment from: Taryn, 25-34 Female (Patient) Published: May 31

I have a very high pain tolerance but this endometrial biopsy is the most painful thing I've ever experienced. I cried on the exam table, sobbed actually; couldn't control it.

Comment from: Angela , 35-44 Female (Patient) Published: May 30

I had my endometrial biopsy done earlier today. My doctor advised of some cramping and to take Motrin beforehand. Well, this experience was terrible! The pain was crazy... I felt so uncomfortable, I was squirming all over the table, and I couldn't help it. I broke out in a sweat and was shaking. She had to go in a 2nd time and I was like, oh boy! She had me stay lying there a few minutes when she was done, so I wouldn't faint. This truly traumatized me, I believe this should have been done in a hospital setting, with medicines!

Comment from: Mel, 35-44 Female (Patient) Published: May 23

Thank goodness I didn’t read the comments first, if I'd known it was going to hurt that much I couldn't have done it! Pure agony. My nurse was my friend and told me later she never saw anyone in the pain I was. I doubt it is because of the doctor and more about whatever is happening inside, i.e., fibroids or something. How other women find that tolerable is beyond me, so that must be the case. I did have Advil before, but didn’t help. I won't do it again awake.

Comment from: K , 35-44 Female (Patient) Published: May 23

I have several hot flashes throughout the day and my obstetrician wants to put me on hormones but wanted to check the nature of my uterine lining hence this morning's endometrial biopsy. I had excruciating cramping during the biopsy. When completed my obstetrician told me to go ahead and get dressed. As I was attempting to even think about getting off the table I was dizzy and knew I was about to faint; which I did. I woke up to the nurses having cool cloth on my face and my neck. This procedure should be done under a local anesthesia. I had pain in my lower back at age 14. I was given ibuprofen and told it was just muscle pain. Then there was nothing till I had a work accident and crushed my lower back and pelvis area at the age of 41. Now I have been told I have ankylosing spondylitis. I have chronic pain every day and night.

Comment from: Hurts, 55-64 (Patient) Published: May 20

I had an endometrial biopsy today. It was horrendous. I'm still in pain even with medicines. To get Mirena placed they said take lots of medicines before, and have someone drive you. Having the Mirena placed hurt for 5 seconds and a tiny bit compared to this. I have hurt throat from screaming. If I need another it will be with anesthesia.

Comment from: Jen, 35-44 Female (Patient) Published: May 15

I am 41 years old and today I had an endometrial biopsy. After reading many comments about the procedure I was terrified to have one. I took 4 Advil tablets 1 hour prior to my appointment and 0.5 of Xanax 30 minutes before. It was a piece of cake. My doctor explained everything she was doing. It was a slight pinch and very light cramping. An hour later I have no pain. Ladies, don’t let the terrible comments scare you! You can do this and it is quick; mine was less than 5 minutes. Good luck!

Comment from: Sweets, 35-44 Female (Patient) Published: May 13

I had an endometrial biopsy this afternoon. Doctor said it is going to be a few seconds but the pain made it feel like I was tortured. My legs were shaking and I almost fainted.

Comment from: eeka, 45-54 Female (Patient) Published: May 10

My endometrial biopsy was a week ago. I concur with many opinions on here: it is barbaric. If men had to endure this procedure it would be pain-free; guaranteed. My pain tolerance is high but I thought I was going to come unglued. I simply was not prepared for what felt like a knife inside. I almost kicked my doctor in the face. He told me I'd experience a pinch and some cramping. What a joke! I still haven't received my results. I am cramping today and have had cramps on and off since.

Comment from: Mel, 35-44 Female (Patient) Published: May 10

I had an endometrial biopsy yesterday and it was unexpected so I took no medicines beforehand. It was very painful and I fainted from the pain. I had severe cramping and bleeding afterward. Today I am super sore and still bleeding. My procedure lasted 15 minutes since none of the instruments were unwrapped before it was started. I see those that commented it wasn't that bad also took anxiety and pain medicines before. I wished that was my case and sure it would have helped.

Comment from: Elizabeth , 45-54 Female (Patient) Published: May 09

I had an endometrial biopsy and I wasn’t even remotely prepared for the excruciating degree of vomit inducing pain. The gynecologist had casually suggested I take some ibuprofen beforehand. It was by far worse pain than even the abortions I’ve had to endure, and was extremely traumatizing for me, as a result. I poured sweat, passed out for a second and was moaning and crying. Ludicrous that they do this procedure with no numbing, especially considering I likely need a D and C, anyway due to hyperplasia.

Comment from: Sara, 45-54 Female (Patient) Published: May 08

I had my 1st endometrial biopsy a few weeks ago, and it was not so bad. I took ibuprofen every 6 hours starting the day before. It felt like bad cramps. She took 8 samples, and I was thinking why the horror stories. Today with a different doctor and a surprise 2nd biopsy said they were going deeper. No ibuprofen, and he said he would stop if painful. I felt like I was being murdered. My buttock was up off the table, leg twisted, holding onto the wall and begging to stop. He didn’t. The 1st biopsy was lower and 2nd super deep. Maybe that’s the difference in pain.

Comment from: bvharper, 55-64 Female (Patient) Published: May 07

I just had an endometrial biopsy a week ago and it was the most painful procedure ever. I broke out in sweats and almost passed out. This is a torture procedure and should not be performed in a doctor’s office. I’m still feeling sore and I am definitely traumatized! Never again.

Comment from: D, 45-54 Female (Patient) Published: May 07

I had endometrial biopsy last week. Horrendous. In this day and age that a woman is dealing with this amount of pain without anesthesia is mind boggling. If you are one of the ladies who only had mild discomfort you should be thankful for that.

Comment from: Notprepared, 45-54 Female (Patient) Published: May 06

I had an endometrial biopsy. I was told the usual story about cramping. It was excruciating! It took my breath away. Not cramping but it felt like a large sharp knife was shoved into my uterus or a bunch of razor blades cutting me up. I swore if I ever had to have one again I was insisting on some IV pain relief. Well, they want to do another and still will give me nothing. It’s torture and barbaric they won’t IV medicate you with some Demerol or Dilaudid and Valium. Knives, not cramps!

Comment from: MSPM, 55-64 Female (Patient) Published: April 26

My first 2 endometrial biopsies were unpleasant, but quite tolerable. Subsequent ones (at least 4) have been torture. Much worse than bad menstrual cramps or labor. Twice I was nauseous and faint afterwards. I have been to 4 different doctors, by the way. A fifth doctor had to stop my pain, it was so bad; I ended up with a D and C. I've had more postmenopausal spotting, and my endometrium is thickened. This time I am asking for a D and C. I can't face the pain again, I shudder.

Comment from: Julie , 35-44 Female (Patient) Published: April 12

I had an endometrial biopsy done 2 days ago and wanted to share my experience as I had a colposcopy this time last year and neither were unbearable pain, just uncomfortable and terrifying. I will add, I have had 4 children so maybe this is why, I don’t know. But I read so much on the internet to scare myself stupid before going in, then it wasn’t all that bad. I just wanted to reassure people that not everyone’s the same so try not to panic. It’s done for a reason, a very good life saving reason.

Comment from: Susan, 35-44 Female (Patient) Published: April 12

I had an endometrial biopsy yesterday and thought it would be like the cervical biopsy... boy, was I wrong! It was, by far, the most painful procedure I have ever experienced (and I have had two children). The pain was so overwhelming that my legs started shaking after the first sample was taken, I threw up and almost passed out. I was crying and gripping the table so hard that I broke all of my fingernails. One day later, I am still throwing up and cramping and bleeding.

Comment from: JS, 55-64 Female (Patient) Published: April 11

I had an endometrial biopsy yesterday. I had been warned that it was quite painful. This was not my experience but I did squeeze my partner’s hand pretty hard. Just a weird feeling, and extremely brief pain, just for seconds. I am a fainter so I took a Xanax ahead of time and 4 Advil tablets but I only had the chance to do that about 20 minutes before the procedure. Maybe that helped. I felt ok today with minor abdominal pain. Hard to know why. I walked for an hour after work, but now I am having chills.

Comment from: Didnot_C_that_coming, 55-64 Female (Patient) Published: April 11

I was experiencing post-menopausal bleeding. The physician’s assistant (PA) explained the procedure but no pre-analgesic was advised. At first it felt like a normal Pap procedure until she had to scrape the endometrial wall. I had instant pain. It was at least a 9 on the pain scale. The PA was great though. She reassured me throughout the procedure. My blood pressure dropped and I felt lightheaded and nauseous. There is still a bit of bleeding, stinging and cramping.

Comment from: Ouch, 35-44 Female (Patient) Published: April 05

I was surprised at the pain from an endometrial biopsy, it was kind of a shock. They go deep! I did not feel well for some time afterward, couldn't eat dinner afterwards but felt better after a few hours.

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